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First bacterial genome created entirely with a computer

ITN News Editor
By ITN News Editor April 5, 2019 13:07

First bacterial genome created entirely with a computer

Scientists in Switzerland have created the world’s first fully computer-generated genome of a living organism, Caulobacter ethensis-2.0.

The synthesised organism is based on the genome of a freshwater bacterium, Caulobacter crescentus, which is a naturally occurring, harmless bacterium.

Its genome contains 4,000 genes of which only about 680 are crucial to the survival of the species in the lab.

The Swiss team, led by Beat Christen, Professor of Experimental Systems Biology at the Swiss Federal Institute of Technology (ETH) Zurich, and his brother, Matthias Christen, a chemist at ETH Zurich, took the minimal genome of C. crescentus as a starting point and set out to chemically synthesise it from scratch.

To create a DNA molecule as large as a bacterial genome, scientists must proceed step by step.

ITN News Editor
By ITN News Editor April 5, 2019 13:07
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