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CRISPR gene editing can cause risky collateral DNA damage

ITN News Editor
By ITN News Editor July 20, 2018 16:42

CRISPR gene editing can cause risky collateral DNA damage

Scientists studying the effects of the potentially game-changing gene editing tool CRISPR/Cas9 have found it can cause unexpected genetic damage which could lead to dangerous changes in some cells.

The findings, published in the journal Nature Biotechnology this week, have safety implications for gene therapies that are being developed using CRISPR/Cas9 – a type of molecular scissor technology that can be used to edit DNA. They also add to findings published last month which suggested the CRISPR gene editing tool may inadvertently make changes in our DNA that increase cancer risk in some cells.

CRISPR/Cas9, one of the newest genome editing tools, can alter sections of DNA in cells by cutting at specific points and introducing changes at that location and is seen by many as a promising way to create treatments for diseases such as HIV or cancer.

ITN News Editor
By ITN News Editor July 20, 2018 16:42

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